9AU3
Crystal structure of GenB2 in complex with G418
Summary for 9AU3
Entry DOI | 10.2210/pdb9au3/pdb |
Descriptor | 6'-epimerase, C-6' aminotransferase, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GENETICIN, ... (5 entities in total) |
Functional Keywords | gentamicin biosynthesis, g418, pyridoxamine-5'-phosphate (pmp), antibiotic |
Biological source | Micromonospora echinospora |
Total number of polymer chains | 1 |
Total formula weight | 45445.84 |
Authors | De Oliveira, G.S.,Bury, P.S.,Huang, F.,Li, Y.,Araujo, N.C.,Zhou, J.,Sun, Y.,Leeper, F.,Leadlay, P.,Dias, M.V.B. (deposition date: 2024-02-28, release date: 2024-09-11) |
Primary citation | Oliveira, G.S.,Dos S Bury, P.,Huang, F.,Li, Y.,Araujo, N.C.,Zhou, J.,Sun, Y.,Leeper, F.J.,Leadlay, P.F.,Dias, M.V.B. Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 2024 Cited by PubMed: 39207862DOI: 10.1021/acschembio.4c00334 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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