9ASH

Cryo-EM structure of the active Lactococcus lactis Csm bound to target in post-cleavage stage

Summary for 9ASH

• Entry DOI: 10.2210/pdb9ash/pdb
• EMDB information: 43814
• Descriptor: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION, CRISPR-associated protein Csm4, ... (11 entities in total)
• Functional Keywords: type iii-a crispr-cas, csm, cyclic oligoadenylate synthesis, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Lactococcus lactis subsp. lactis; More
• Total number of polymer chains: 13
• Total formula weight: 333638.46

Authors

Wang, B.,Goswami, H.N.,Li, H. (deposition date: 2024-02-25, release date: 2024-08-14)

• Primary citation: Goswami, H.N.,Ahmadizadeh, F.,Wang, B.,Addo-Yobo, D.,Zhao, Y.,Whittington, A.C.,He, H.,Terns, M.P.,Li, H.; Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production.; Nucleic Acids Res., 2024; PubMed: 38989619; DOI: 10.1093/nar/gkae603

Experimental method