9ASH

Cryo-EM structure of the active Lactococcus lactis Csm bound to target in post-cleavage stage

9ASH の概要

• エントリーDOI: 10.2210/pdb9ash/pdb
• EMDBエントリー: 43814
• 分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION, CRISPR-associated protein Csm4, ... (11 entities in total)
• 機能のキーワード: type iii-a crispr-cas, csm, cyclic oligoadenylate synthesis, rna binding protein-rna complex, rna binding protein/rna
• 由来する生物種: Lactococcus lactis subsp. lactis; 詳細
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 333638.46

構造登録者

Wang, B.,Goswami, H.N.,Li, H. (登録日: 2024-02-25, 公開日: 2024-08-14)

• 主引用文献: Goswami, H.N.,Ahmadizadeh, F.,Wang, B.,Addo-Yobo, D.,Zhao, Y.,Whittington, A.C.,He, H.,Terns, M.P.,Li, H.; Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production.; Nucleic Acids Res., 2024; PubMed: 38989619; DOI: 10.1093/nar/gkae603

実験手法