9AR5

Structure of Acidothermus cellulolyticus Cas9 bound with methylated DNA

Summary for 9AR5

• Entry DOI: 10.2210/pdb9ar5/pdb
• EMDB information: 43770
• Descriptor: CRISPR-associated endonuclease, Csn1 family, RNA (92-MER), DNA (25-MER), ... (4 entities in total)
• Functional Keywords: crispr-cas9, methylated dna, acecas9, hnh rotation, dna binding protein-dna-rna complex, dna binding protein/dna/rna
• Biological source: Acidothermus cellulolyticus; More
• Total number of polymer chains: 4
• Total formula weight: 172765.61

Authors

Das, A.,Rai, J.,Wang, B.,Li, H. (deposition date: 2024-02-22, release date: 2025-02-26)

• Primary citation: Roth, M.O.,Shu, Y.,Zhao, Y.,Trasanidou, D.,Hoffman, R.D.,Trasanidis, N.,Gelasco, M.K.,Medina, M.L.,Das, D.,Rai, J.,Wang, B.,Li, H.; Molecular Basis for Epigenetic-sensitive Editing by Cas9; To be Published,

Experimental method

ELECTRON MICROSCOPY (2.88 Å)