9XZG

Cryo-EM structure of ALK in complex with CRBN/DDB1 and TRI-611

This is a non-PDB format compatible entry.

Summary for 9XZG

• Entry DOI: 10.2210/pdb9xzg/pdb
• EMDB information: 72353
• Descriptor: Protein cereblon, ALK tyrosine kinase receptor, ZINC ION, ... (4 entities in total)
• Functional Keywords: dna binding protein-transferase complex, dna binding protein, ternary complex, molecular glue, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 87294.96

Authors

Bart, A.G.,Kamadurai, H.B. (deposition date: 2025-08-27, release date: 2026-08-05)

• Primary citation: Bart, A.G.,Kamadurai, H.B.; Cryo-EM structure of ALK in complex with CRBN/DDB1 and TRI-611; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)