9Q0O

Cryo-EM structure of PPAT-NUDT5 complex bound to 6-benzylthioinosine-5'-monophosphate (6-benzylTIMP)

This is a non-PDB format compatible entry.

Summary for 9Q0O

• Entry DOI: 10.2210/pdb9q0o/pdb
• Related: 9Q0M 9Q0N
• EMDB information: 72099 72100 72101
• Descriptor: Amidophosphoribosyltransferase, ADP-sugar pyrophosphatase, IRON/SULFUR CLUSTER, ... (4 entities in total)
• Functional Keywords: purine synthesis, phosphoribosyltransferase, biosynthetic protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 344080.00

Authors

Witus, S.R.W.,Yang, Z.,Rape, M. (deposition date: 2025-08-13, release date: 2026-06-03)

• Primary citation: Witus, S.R.W.,Kober, M.M.,Roh, H.,Yang, Z.,Choueiry, F.,Ghate, A.,Titov, D.V.,Rape, M.; Regulation of purine synthesis and chemotherapy response by metabolite-derived molecular glues; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)