9MZC

anti-IL6 designed Fab

Summary for 9MZC

• Entry DOI: 10.2210/pdb9mzc/pdb
• Related: 9MUY 9MUZ 9MVJ
• Descriptor: anti-IL6 designed Fab heavy chain, anti-IL6 designed Fab light chain, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: design, immune system, pharmacology, antibody, machine learning
• Biological source: Rattus norvegicus (rat); More
• Total number of polymer chains: 2
• Total formula weight: 48986.37

Authors

Kiefer, J.R.,Alberstein, R.G.,Frey, N.C.,Seeger, F.,Dou, Y.,Huo, C.,Watkins, A.M.,Leaver-Fay, A.,Hofmann, J.L.,Gligorijevic, V.,Bonneau, R. (deposition date: 2025-01-22, release date: 2026-09-09)

• Primary citation: Kiefer, J.R.,Alberstein, R.G.,Frey, N.C.,Seeger, F.,Dou, Y.,Huo, C.,Watkins, A.M.,Leaver-Fay, A.,Hofmann, J.L.,Gligorijevic, V.,Bonneau, R.; Lab-in-the-loop therapeutic antibody design with deep learning; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.58 Å)