9MVJ

anti-EGFR designed Fab

Summary for 9MVJ

• Entry DOI: 10.2210/pdb9mvj/pdb
• Related: 9MUY 9MUZ
• Descriptor: anti-EGFR designed Fab heavy chain, anti-EGFR designed Fab light chain, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: antibody, design, machine learning, fab, immune system
• Biological source: Rattus norvegicus (rat); More
• Total number of polymer chains: 2
• Total formula weight: 49627.12

Authors

Kiefer, J.R.,Frey, N.C.,Alberstein, R.G.,Seeger, F.,Watkins, A.M.,Gligorijevic, V.,Dou, Y.,Tang, Y.,Regev, A.,Bonneau, R. (deposition date: 2025-01-15, release date: 2026-09-09)

• Primary citation: Frey, N.C.,Seeger, F.,Kiefer, J.R.,Alberstein, R.G.,Watkins, A.M.,Bonneau, R.,Regev, A.,Hotzel, I.; Lab-in-the-loop therapeutic antibody design with deep learning; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)