9LRN

The crystal structure of PDE2A with 13t

This is a non-PDB format compatible entry.

Summary for 9LRN

• Entry DOI: 10.2210/pdb9lrn/pdb
• Descriptor: cGMP-dependent 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: pde2 complexed with inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 425278.79

Authors

Huang, Y.-Y.,Luo, H.-B. (deposition date: 2025-01-31, release date: 2026-05-27)

• Primary citation: Xu, C.,Huang, Y.-Y.,Luo, H.-B.; Discovery of A phosphodiesterase 2 Inhibitor Containing 6-fluoroquinoline-8-carboxamide Moiety for the Treatment of Alzheimer's disease; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)