9IEX
Human Deoxyhypusine Synthase Fragment Screening Campaign - VT0155 follow-up ligand DMP7
This is a non-PDB format compatible entry.
Summary for 9IEX
| Entry DOI | 10.2210/pdb9iex/pdb |
| Descriptor | Deoxyhypusine synthase, 6-[2-oxidanylidene-2-(11-oxidanylidene-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl)ethyl]-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-11-one, ... (4 entities in total) |
| Functional Keywords | fragment screening, polyamines, high-throughput, posttranslational modifications, transferase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 177352.97 |
| Authors | |
| Primary citation | Wilk, P.,Wator-Wilk, E.,Muszak, D.,Kochanowski, P.,Krojer, T.,Grudnik, P. Crystallographic fragment screening supports tool compound discovery and reveals conformational flexibility in human deoxyhypusine synthase To Be Published, |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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