9F33

Cryo-EM structure of Dopamine 3 Receptor:Go complex bound to bitopic FOB02-04A - Conformation A

This is a non-PDB format compatible entry.

Summary for 9F33

• Entry DOI: 10.2210/pdb9f33/pdb
• EMDB information: 50168
• Descriptor: Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, dopamine, bitopic, receptor, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 191428.30

Authors

Arroyo-Urea, S.,Garcia-Nafria, J. (deposition date: 2024-04-24, release date: 2024-09-18)

• Primary citation: Arroyo-Urea, S.,Nazarova, A.L.,Carrion-Antoli, A.,Bonifazi, A.,Battiti, F.O.,Lam, J.H.,Newman, A.H.,Katritch, V.,Garcia-Nafria, J.; A bitopic agonist bound to the dopamine 3 receptor reveals a selectivity site.; Nat Commun, 15:7759-7759, 2024; PubMed: 39237617; DOI: 10.1038/s41467-024-51993-4

Experimental method

ELECTRON MICROSCOPY (3.05 Å)