9EC3

Cryo-EM structure of the ribosome-tunnel occluding hibernation factor bound to the Mycobacterium tuberculosis C- 70S ribosome carrying fMet-tRNA(fMet) and deacylated tRNA at ribosome P and E sites.

This is a non-PDB format compatible entry.

Summary for 9EC3

• Entry DOI: 10.2210/pdb9ec3/pdb
• Related: 9E16 9E1S 9EBB
• EMDB information: 47899
• Descriptor: E-tRNA, fMet-tRNA(fMet), 50S ribosomal protein L2, 50S ribosomal protein L3, ... (54 entities in total)
• Functional Keywords: hibernating ribosome, mycobacterium tuberculosis, nascent peptide exit tunnel, 70s, hibernation factor, translation, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 55
• Total formula weight: 2305905.34

Authors

Majumdar, S.,Ojha, A.K.,Agrawal, R.K. (deposition date: 2024-11-13, release date: 2026-09-02)

• Primary citation: Majumdar, S.,Li, Y.,Manjari, S.R.,Gamper, H.B.,Hou, Y.M.,Banavali, N.K.,Ojha, A.K.,Agrawal, R.K.; A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis; Biorxiv, 2024; DOI: 10.1101/2024.11.25.625233

Experimental method

ELECTRON MICROSCOPY (3.29 Å)