9EC3
Cryo-EM structure of the ribosome-tunnel occluding hibernation factor bound to the Mycobacterium tuberculosis C- 70S ribosome carrying fMet-tRNA(fMet) and deacylated tRNA at ribosome P and E sites.
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00049 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtvkerrrp.DGsyikFdeNaaVI |
| Chain | Residue | Details |
| K | ALA60-ILE86 |
| site_id | PS00050 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L23 Ribosomal protein L23 signature. KRAIVTLApgsrpidL |
| Chain | Residue | Details |
| T | LYS80-LEU95 |
| site_id | PS00052 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_S7 Ribosomal protein S7 signature. SqLvtqLVnkvllkGKKslaerIVygA |
| Chain | Residue | Details |
| g | SER20-ALA46 |
| site_id | PS00053 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GvaIISTSsGLLtdrqAA |
| Chain | Residue | Details |
| h | GLY102-ALA119 |
| site_id | PS00054 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. IrSLqaA.GLeVgaisDvTPqPHN |
| Chain | Residue | Details |
| k | ILE107-ASN129 |
| site_id | PS00055 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR |
| Chain | Residue | Details |
| l | LYS43-ARG50 |
| site_id | PS00056 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDrVsLmEtRPLS |
| Chain | Residue | Details |
| q | GLY109-SER121 |
| site_id | PS00057 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_S18 Ribosomal protein S18 signature. VDYkd.TatLrvFISDr.GKIrsrGV |
| Chain | Residue | Details |
| r | VAL26-VAL49 |
| site_id | PS00323 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S19 Ribosomal protein S19 signature. DGRkhvpvfVtesmVGhkLGEFapT |
| Chain | Residue | Details |
| s | ASP53-THR77 |
| site_id | PS00360 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGpsGQagAlrlGiARAL |
| Chain | Residue | Details |
| i | GLY90-LEU108 |
| site_id | PS00361 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_S10 Ribosomal protein S10 signature. VvrtGAsvvGPVpLPT |
| Chain | Residue | Details |
| j | VAL29-THR44 |
| site_id | PS00362 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. LteHLkvhKhDhhSrrgLllLvgrrrrLikY |
| Chain | Residue | Details |
| o | LEU39-TYR69 |
| site_id | PS00464 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L22 Ribosomal protein L22 signature. KriRpRAqGRafrirrrtSHITVvV |
| Chain | Residue | Details |
| S | LYS93-VAL117 |
| site_id | PS00467 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PsvRGVVmNPvD |
| Chain | Residue | Details |
| C | PRO219-ASP230 |
| site_id | PS00474 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FadgsyvDvtGtSkGKGfaGtmkR |
| Chain | Residue | Details |
| D | PHE106-ARG129 |
| site_id | PS00475 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGdGkLtak..VdVsahkFSgsArakItaaG |
| Chain | Residue | Details |
| L | LYS110-GLY140 |
| site_id | PS00525 |
| Number of Residues | 9 |
| Details | RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PDpYKGKGV |
| Chain | Residue | Details |
| G | PRO155-VAL163 |
| site_id | PS00548 |
| Number of Residues | 35 |
| Details | RIBOSOMAL_S3 Ribosomal protein S3 signature. SRsefyreGrVplHt..LradIDyglyeakTtfGriG |
| Chain | Residue | Details |
| c | SER163-GLY197 |
| site_id | PS00579 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. NNRRLRtVRQEIARI |
| Chain | Residue | Details |
| Y | ASN43-ILE57 |
| site_id | PS00582 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L33 Ribosomal protein L33 signature. YtTrKNrrndPdrLIlrKYD |
| Chain | Residue | Details |
| b | TYR21-ASP40 |
| site_id | PS00585 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfsFtAlvIVGDgn.GmVGvGygkak.EVpa.AI |
| Chain | Residue | Details |
| e | GLY59-ILE91 |
| site_id | PS00586 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWINIFP |
| Chain | Residue | Details |
| M | LYS59-PRO70 |
| site_id | PS00632 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvIYRaglArTrrmARqLV |
| Chain | Residue | Details |
| d | LEU89-VAL113 |
| site_id | PS00634 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_L30 Ribosomal protein L30 signature. SLrtLgLrRirHsVirednaatrgLIavVrhLV |
| Chain | Residue | Details |
| Z | SER22-VAL54 |
| site_id | PS00646 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_S13_1 Ribosomal protein S13 signature. QGlRHrrGmpVRGQ |
| Chain | Residue | Details |
| m | GLN88-GLN101 |
| site_id | PS00651 |
| Number of Residues | 28 |
| Details | RIBOSOMAL_L9 Ribosomal protein L9 signature. GsiGdtveVkdGYgrNFLlprglAivaS |
| Chain | Residue | Details |
| H | GLY13-SER40 |
| site_id | PS00701 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGsGKGspewW |
| Chain | Residue | Details |
| M | ARG82-TRP93 |
| site_id | PS00732 |
| Number of Residues | 10 |
| Details | RIBOSOMAL_S16 Ribosomal protein S16 signature. VkIKLTRLGK |
| Chain | Residue | Details |
| p | VAL3-LYS12 |
| site_id | PS00783 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L13 Ribosomal protein L13 signature. ILGMLPknrl.SRqiqrkLrVYaG |
| Chain | Residue | Details |
| J | ILE105-GLY127 |
| site_id | PS00784 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpnnrrRarvh.GFrlR |
| Chain | Residue | Details |
| 2 | LYS5-ARG24 |
| site_id | PS00828 |
| Number of Residues | 26 |
| Details | RIBOSOMAL_L36 Ribosomal protein L36 signature. CdkCrlIrRhgrVmViCsdp.RHkQrQ |
| Chain | Residue | Details |
| 4 | CYS11-GLN36 |
| site_id | PS00831 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L27 Ribosomal protein L27 signature. GeILvRQRGtkfhpG |
| Chain | Residue | Details |
| W | GLY34-GLY48 |
| site_id | PS00936 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHsGAsKRFrrtgtgkivrqkanr.RH |
| Chain | Residue | Details |
| 3 | LYS5-HIS31 |
| site_id | PS00937 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L20 Ribosomal protein L20 signature. KgefRkLWIARINaaaR |
| Chain | Residue | Details |
| Q | LYS54-ARG70 |
| site_id | PS01015 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L19 Ribosomal protein L19 signature. VvTrGDVR.RAKLYYLR |
| Chain | Residue | Details |
| P | VAL85-ARG100 |
| site_id | PS01048 |
| Number of Residues | 10 |
| Details | RIBOSOMAL_S6 Ribosomal protein S6 signature. GkRRLAYeIA |
| Chain | Residue | Details |
| f | GLY44-ALA53 |
| site_id | PS01108 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtVlVIsGkdKGak.GkV |
| Chain | Residue | Details |
| U | GLY6-VAL23 |
| site_id | PS01143 |
| Number of Residues | 22 |
| Details | RIBOSOMAL_L31 Ribosomal protein L31 signature. EVcsqcHPFYTgkqkildsg....GR |
| Chain | Residue | Details |
| 6 | GLU36-ARG57 |
| site_id | PS01167 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L17 Ribosomal protein L17 signature. ItTTepKaRalrpyaEkLIThAK |
| Chain | Residue | Details |
| N | ILE34-LYS56 |
| site_id | PS01169 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L21 Ribosomal protein L21 signature. IrihKfknKTgyhkrqGHRQqlT |
| Chain | Residue | Details |
| R | ILE74-THR96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 23 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
