9BF6
Cryo-EM structure of the HIV-1 WITO IDL Env trimer in complex with PGT122 Fab
Summary for 9BF6
Entry DOI | 10.2210/pdb9bf6/pdb |
EMDB information | 44482 44484 44491 |
Descriptor | Envelope glycoprotein gp41, Envelope glycoprotein gp120, PGT122 heavy chain, ... (9 entities in total) |
Functional Keywords | cd4, hiv-1, sosip, vaccine, gp120, gp41, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 (HIV-1) More |
Total number of polymer chains | 12 |
Total formula weight | 318185.17 |
Authors | |
Primary citation | Zhang, P.,Gorman, J.,Tsybovsky, Y.,Lu, M.,Liu, Q.,Gopan, V.,Singh, M.,Lin, Y.,Miao, H.,Seo, Y.,Kwon, A.,Olia, A.S.,Chuang, G.Y.,Geng, H.,Lai, Y.T.,Zhou, T.,Mascola, J.R.,Mothes, W.,Kwong, P.D.,Lusso, P. Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43:114518-114518, 2024 Cited by PubMed: 39028623DOI: 10.1016/j.celrep.2024.114518 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
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