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8ZRK

Cryo-EM structure of GPR119-Gs Complex with small molecule agonist GSK-1292263

This is a non-PDB format compatible entry.
Summary for 8ZRK
Entry DOI10.2210/pdb8zrk/pdb
EMDB information60399
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywordsgpr119, gsk-1292263, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains5
Total formula weight154418.31
Authors
Wong, T.S.,Xiong, T.T.,Zeng, Z.C.,Gan, S.Y.,Qiu, C.,Du, Y. (deposition date: 2024-06-04, release date: 2024-06-19)
Primary citationWong, T.S.,Xiong, T.T.,Zeng, Z.C.
Cryo-EM structure of GPR119-Gs complex
To be published,
Experimental method
ELECTRON MICROSCOPY (2.82 Å)
Structure validation

222624

數據於2024-07-17公開中

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