8ZOY

Cryo-EM structure of human norepinephrine transporter NET bound with norepinephrine in an inward open state at a resolution of 2.5 angstrom

Summary for 8ZOY

Entry DOI	10.2210/pdb8zoy/pdb
Related	8ZP1 8ZP2
EMDB information	60322 60324 60325
Descriptor	Sodium-dependent noradrenaline transporter, Nb_BF9, L-NOREPINEPHRINE, ... (6 entities in total)
Functional Keywords	norepinephrine transport, norepinephrine, transport protein/immune system, transport protein-immune system complex
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	78634.06
Authors	Song, A.L.,Wu, X.D. (deposition date: 2024-05-29, release date: 2024-09-11, Last modification date: 2024-10-16)
Primary citation	Song, A.,Wu, X. Mechanistic insights of substrate transport and inhibitor binding revealed by high-resolution structures of human norepinephrine transporter. Cell Res., 2024 Cited by PubMed: 39223283 DOI: 10.1038/s41422-024-01024-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation