8ZLO
F0502B-bound E46K alpha-synuclein fibril
Summary for 8ZLO
Entry DOI | 10.2210/pdb8zlo/pdb |
EMDB information | 60231 |
Descriptor | Alpha-synuclein, 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol (2 entities in total) |
Functional Keywords | amyloid fibril, complex, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 69479.67 |
Authors | |
Primary citation | Liu, K.,Tao, Y.,Zhao, Q.,Xia, W.,Li, X.,Zhang, S.,Yao, Y.,Xiang, H.,Han, C.,Tan, L.,Sun, B.,Li, D.,Li, A.,Liu, C. Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils. Proc.Natl.Acad.Sci.USA, 121:e2321633121-e2321633121, 2024 Cited by PubMed: 39172784DOI: 10.1073/pnas.2321633121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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