8ZK8

Crystal structure of the Decarboxylase KDC4427 mutant E468L in complex with indole-3-pyruvic acid

Summary for 8ZK8

• Entry DOI: 10.2210/pdb8zk8/pdb
• Descriptor: Indolepyruvate decarboxylase, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: decarboxylase, lyase
• Biological source: Enterobacter sp. CGMCC 5087
• Total number of polymer chains: 2
• Total formula weight: 125188.36

Authors

Dong, S.,Liu, L.,Zhang, H. (deposition date: 2024-05-15, release date: 2025-05-21, Last modification date: 2026-05-20)

• Primary citation: Dong, S.,Liu, L.,Yang, Y.,Liao, W.,Zhang, X.,Ling, C.,Han, Y.,Wang, L.,Zhang, H.; Mechanistic Insights into the Substrate Promiscuity of alpha-Ketoacid Decarboxylases for Enhanced Higher-Alcohol Biosynthesis; Acs Sustain Chem Eng, 2026; DOI: 10.1021/acssuschemeng.5c13943

Experimental method

X-RAY DIFFRACTION (2.16 Å)