8ZK1

Cryo-EM structure of BTN2A1-BTN3A1-BTN3A2 mutant complex (BTN3A1 H381R, BTN2A1 R477A/T510A)

Summary for 8ZK1

• Entry DOI: 10.2210/pdb8zk1/pdb
• EMDB information: 60163
• Descriptor: Butyrophilin subfamily 2 member A1, Butyrophilin subfamily 3 member A2, Butyrophilin subfamily 3 member A1 (3 entities in total)
• Functional Keywords: receptor, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 218346.97

Authors

Xin, W.,Huang, B.,Su, Q.,Zhou, Q. (deposition date: 2024-05-15, release date: 2025-11-26)

• Primary citation: Xin, W.,Huang, B.,Gao, W.,Zhang, W.,Hu, Y.,Liu, Y.,Liang, E.,Shi, Y.,Su, Q.,Zhou, Q.; Phosphoantigen-Driven Dissociation of Butyrophilin Oligomers Activates gamma delta T Cells; Biorxiv, 2025; DOI: 10.1101/2025.09.26.677252

Experimental method

ELECTRON MICROSCOPY (3.8 Å)