8ZK0

Cryo-EM structure of the full length pAg-bound BTN2A1-BTN3A1-BTN3A2 in complex with Vgamma9-Vdelta2 TCR (G115 genotype)

Summary for 8ZK0

• Entry DOI: 10.2210/pdb8zk0/pdb
• EMDB information: 60162
• Descriptor: Butyrophilin subfamily 2 member A1, T cell receptor delta variable 2, T cell receptor delta constant 1, T cell receptor gamma variable 9, T cell receptor gamma constant 1, ... (6 entities in total)
• Functional Keywords: receptor, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 273725.62

Authors

Xin, W.,Huang, B.,Su, Q.,Zhou, Q. (deposition date: 2024-05-15, release date: 2025-11-26)

• Primary citation: Xin, W.,Huang, B.,Gao, W.,Zhang, W.,Hu, Y.,Liu, Y.,Liang, E.,Shi, Y.,Su, Q.,Zhou, Q.; Phosphoantigen-Driven Dissociation of Butyrophilin Oligomers Activates gamma delta T Cells; Biorxiv, 2025; DOI: 10.1101/2025.09.26.677252

Experimental method

ELECTRON MICROSCOPY (3.4 Å)