8ZEB

Crystal structure of BCL-XL bound by cp-B6X-4

Summary for 8ZEB

• Entry DOI: 10.2210/pdb8zeb/pdb
• Descriptor: Bcl-2-like protein 1, THR-PRO-GLU-TRP-ALA-SER-THR-LEU-ARG-PRO-GLU-(CCS)-(EDN)-(Z7Z)-(PRS) (3 entities in total)
• Functional Keywords: bcl-xl, cyclic peptide, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 35948.28

Authors

Sun, X.N.,Liu, J.X.,Wu, D.L. (deposition date: 2024-05-05, release date: 2025-01-29)

• Primary citation: Liu, J.J.,Sun, X.N.,Zhuang, J.,Liu, Z.Y.,Xu, C.Y.,Wu, D.L.,Wu, C.L.; Biphenyl-Dihydrothiazole-Cyclized Peptide Libraries for Peptide Lig-and and Drug Discovery; Sci China Chem, 2025; DOI: 10.1007/s11426-024-2291-x

Experimental method

X-RAY DIFFRACTION (1.95 Å)