8ZCK

Serial Femtosecond Crystallography Structure of Fc Fragment of Human IgG1 from Biosimilar VEGF-Trap

Summary for 8ZCK

Entry DOI	10.2210/pdb8zck/pdb
Descriptor	Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	fusion protein, immunoglobulin, n-glycans, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	50155.00
Authors	Destan, E.,DeMirci, H. (deposition date: 2024-04-30, release date: 2024-05-08)
Primary citation	Destan, E.,Demirci, H. Serial Femtosecond Crystallography Structure of Fc Fragment of Human IgG1 from VEGF-Trap To Be Published,
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation