8ZC9

The Cryo-EM structure of DSR2-Tail tube-NAD+ complex

Summary for 8ZC9

Entry DOI	10.2210/pdb8zc9/pdb
EMDB information	39925
Descriptor	SIR2-like domain-containing protein, tail tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	nadase, anti-phage defense, tail-tube protein, nad, immune system
Biological source	Bacillus subtilis More
Total number of polymer chains	6
Total formula weight	535538.01
Authors	Wang, R.,Xu, Q.,Wu, Z.,Li, J.,Yang, R.,Shi, Z.,Li, F. (deposition date: 2024-04-29, release date: 2024-09-11)
Primary citation	Wang, R.,Xu, Q.,Wu, Z.,Li, J.,Guo, H.,Liao, T.,Shi, Y.,Yuan, L.,Gao, H.,Yang, R.,Shi, Z.,Li, F. The structural basis of the activation and inhibition of DSR2 NADase by phage proteins. Nat Commun, 15:6185-6185, 2024 Cited by PubMed: 39039073 DOI: 10.1038/s41467-024-50410-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.14 Å)

Structure validation