8ZC8

The structure of MitM and mitomycin A with SAH in mitomycin

Summary for 8ZC8

• Entry DOI: 10.2210/pdb8zc8/pdb
• Descriptor: MitM, S-ADENOSYL-L-HOMOCYSTEINE, [(1aS,8S,8aR,8bS)-6,8a-dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate, ... (4 entities in total)
• Functional Keywords: sam-dependent methyltransferase, transferase
• Biological source: Streptomyces caespitosus
• Total number of polymer chains: 2
• Total formula weight: 63288.60

Authors

Xia, M.,Dong, D. (deposition date: 2024-04-28, release date: 2024-11-27, Last modification date: 2025-04-09)

• Primary citation: Xia, M.,Dong, D.; Crystallographic analysis of MitM, which catalyzes the post-mitosane modification in mitomycin biosynthesis; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)