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8ZAX

Crystal structure of a short-chain dehydrogenase from Lactobacillus fermentum with NADPH

Summary for 8ZAX
Entry DOI10.2210/pdb8zax/pdb
DescriptorSDR family oxidoreductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywordsshort-chain dehydrogenase, lactobacillus fermentum, hydrolase
Biological sourceLimosilactobacillus fermentum
Total number of polymer chains2
Total formula weight54132.67
Authors
Wang, J.J.,Cong, L.,Wei, H.L.,Liu, W.D.,You, S. (deposition date: 2024-04-25, release date: 2024-10-30)
Primary citationWang, Q.,Cong, L.,Guo, J.,Wang, J.,Han, X.,Zhang, W.,Liu, W.,Wei, H.,You, S.
Structure-Guided Engineering of a Short-Chain Dehydrogenase LfSDR1 for Efficient Biosynthesis of (R)-9-(2-Hydroxypropyl)adenine, the Key Intermediate of Tenofovir
Adv.Synth.Catal., 2024
Cited by
DOI: 10.1002/adsc.202400752
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.54 Å)
Structure validation

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PDB entries from 2024-11-20

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