8ZAX
Crystal structure of a short-chain dehydrogenase from Lactobacillus fermentum with NADPH
Summary for 8ZAX
Entry DOI | 10.2210/pdb8zax/pdb |
Descriptor | SDR family oxidoreductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | short-chain dehydrogenase, lactobacillus fermentum, hydrolase |
Biological source | Limosilactobacillus fermentum |
Total number of polymer chains | 2 |
Total formula weight | 54132.67 |
Authors | Wang, J.J.,Cong, L.,Wei, H.L.,Liu, W.D.,You, S. (deposition date: 2024-04-25, release date: 2024-10-30) |
Primary citation | Wang, Q.,Cong, L.,Guo, J.,Wang, J.,Han, X.,Zhang, W.,Liu, W.,Wei, H.,You, S. Structure-Guided Engineering of a Short-Chain Dehydrogenase LfSDR1 for Efficient Biosynthesis of (R)-9-(2-Hydroxypropyl)adenine, the Key Intermediate of Tenofovir Adv.Synth.Catal., 2024 Cited by DOI: 10.1002/adsc.202400752PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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