8Z1H

Crystal structure of SARS main protease in complex with PF-00835231

Summary for 8Z1H

• Entry DOI: 10.2210/pdb8z1h/pdb
• Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 2
• Total formula weight: 66706.16

Authors

Lin, C.,Zhang, J.,Li, J. (deposition date: 2024-04-11, release date: 2025-03-19)

• Primary citation: Lin, C.,Zhang, J.,Li, J.; Crystal structure of SARS main protease in complex with PF-00835231; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.61 Å)