8YX9

CD40 in complex with Dacetuzumab Fab

8YX9 の概要

• エントリーDOI: 10.2210/pdb8yx9/pdb
• 分子名称: Dacetuzumab, Heavy chain, Dacetuzumab, light chain, Tumor necrosis factor receptor superfamily member 5, ... (5 entities in total)
• 機能のキーワード: cd40, dacetuzumab, bleselumab, agonist activity, tumor necrosis factor, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 272247.54

構造登録者

Caaveiro, J.M.M.,Fernandez-Perez, J.,Tsumoto, K. (登録日: 2024-04-02, 公開日: 2024-05-08, 最終更新日: 2024-05-22)

• 主引用文献: Asano, R.,Nakakido, M.,Perez, J.F.,Ise, T.,Caaveiro, J.M.M.,Nagata, S.,Tsumoto, K.; Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.; Biochem.Biophys.Res.Commun., 714:149969-149969, 2024; PubMed: 38657446; DOI: 10.1016/j.bbrc.2024.149969

実験手法

X-RAY DIFFRACTION (2.8 Å)