8YTA

The crystal structure of PDE8A with 1604R

This is a non-PDB format compatible entry.

Summary for 8YTA

• Entry DOI: 10.2210/pdb8yta/pdb
• Descriptor: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: pde8 inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 41999.89

Authors

Huang, Y.-Y.,Luo, H.-B. (deposition date: 2024-03-25, release date: 2025-10-22)

• Primary citation: Huang, Y.-Y.,Luo, H.-B.; Targeting phosphodiesterase 8A (PDE8A) to boost adipogenesis and hair cycling; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5000125483 Å)