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8YRA

The Cyro-EM Structure of human SLC26A3 with specific inhibitor DRAinh-A250

This is a non-PDB format compatible entry.
Summary for 8YRA
Entry DOI10.2210/pdb8yra/pdb
Related8YR9
EMDB information39538 39539
DescriptorChloride anion exchanger, CHOLESTEROL HEMISUCCINATE, 2-[7-[(3-bromophenyl)methoxy]-4,8-dimethyl-2-oxidanylidene-chromen-3-yl]ethanoic acid (3 entities in total)
Functional Keywordschloride anion exchanger, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight173911.35
Authors
Feng, J.R.,Dang, S. (deposition date: 2024-03-20, release date: 2025-09-24)
Primary citationFeng, J.R.,Dang, S.
Structural Insights into the Inhibition Mechanism of Human DRA
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.78 Å)
Structure validation

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PDB entries from 2026-01-28

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