8YR7

Crystal structure of human dishevelled 2 (Dvl2) PDZ domain fused with WGEF internal peptide motif

8YR7 の概要

• エントリーDOI: 10.2210/pdb8yr7/pdb
• 分子名称: Segment polarity protein dishevelled homolog DVL-2,Rho guanine nucleotide exchange factor 19 (1 entity in total)
• 機能のキーワード: wnt signaling, signaling protein
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11607.19

構造登録者

Omble, A.,Mahajan, S.,Kulkarni, K.A. (登録日: 2024-03-20, 公開日: 2024-05-29)

• 主引用文献: Omble, A.,Mahajan, S.,Bhoite, A.,Kulkarni, K.; Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.; Commun Biol, 7:543-543, 2024; PubMed: 38714795; DOI: 10.1038/s42003-024-06194-6

実験手法

X-RAY DIFFRACTION (3 Å)