8YOX

Crystal structure of hFSP1 with 6-OH-FAD (hFSP1-6-OH-FAD)

Summary for 8YOX

Entry DOI	10.2210/pdb8yox/pdb
Descriptor	Ferroptosis suppressor protein 1, 6-HYDROXY-FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... (4 entities in total)
Functional Keywords	flavoprotein, 6-oh-fad, redox, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	40932.68
Authors	Lan, H.Y.,Gao, Y.,Hong, T.,Zhao, Z.Z.,Chang, Z.H.,Wang, Y.F.,Wang, F. (deposition date: 2024-03-14, release date: 2025-01-08)
Primary citation	Lan, H.,Gao, Y.,Hong, T.,Chang, Z.,Zhao, Z.,Wang, Y.,Wang, F. Structural insight into 6-OH-FAD-dependent activation of hFSP1 for ferroptosis suppression. Cell Discov, 10:88-88, 2024 Cited by PubMed: 39160155 DOI: 10.1038/s41421-024-00723-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation