8YOQ
Crystal structure of hFSP1 with both 6-OH-FAD and NADP (hFSP1-6-OH-FAD-NADP)
Summary for 8YOQ
| Entry DOI | 10.2210/pdb8yoq/pdb |
| Descriptor | Ferroptosis suppressor protein 1, 6-HYDROXY-FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | flavoprotein, 6-oh-fad, redox, nadp, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 41678.10 |
| Authors | Lan, H.Y.,Gao, Y.,Hong, T.,Zhao, Z.Z.,Chang, Z.H.,Wang, Y.F.,Wang, F. (deposition date: 2024-03-13, release date: 2025-01-08) |
| Primary citation | Lan, H.,Gao, Y.,Hong, T.,Chang, Z.,Zhao, Z.,Wang, Y.,Wang, F. Structural insight into 6-OH-FAD-dependent activation of hFSP1 for ferroptosis suppression. Cell Discov, 10:88-88, 2024 Cited by PubMed: 39160155DOI: 10.1038/s41421-024-00723-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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