8YO2

Metallo-beta-lactamase VIM-2 in Complex with MBL Inhibitor B4

This is a non-PDB format compatible entry.

Summary for 8YO2

• Entry DOI: 10.2210/pdb8yo2/pdb
• Descriptor: Metallo-beta-lactamase VIM-2, ZINC ION, 2-[[(3~{R})-6-chloranyl-1,1-bis(oxidanyl)-3~{H}-2,1$l^{4}-benzoxaborol-3-yl]methyl]prop-2-enoic acid, ... (4 entities in total)
• Functional Keywords: beta-lactamase, carbapenemase, metal binding protein-inhibitor complex, metal binding protein/inhibitor
• Biological source: Enterobacteriaceae
• Total number of polymer chains: 2
• Total formula weight: 50333.60

Authors

Wang, S.Y.,Wang, S.Y. (deposition date: 2024-03-12, release date: 2025-03-19)

• Primary citation: Liang, G.Q.,Wang, S.Y.,Li, G.B.; Discovery of 2-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)methyl)acrylic acids as potent MBL inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.498 Å)