8YN2
Cryo-EM structure of histamine H1 receptor in complex with histamine and miniGq
Summary for 8YN2
Entry DOI | 10.2210/pdb8yn2/pdb |
EMDB information | 39412 |
Descriptor | Engineered guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, signaling protein |
Biological source | synthetic construct More |
Total number of polymer chains | 5 |
Total formula weight | 186918.89 |
Authors | |
Primary citation | Zhang, X.,Liu, G.,Zhong, Y.N.,Zhang, R.,Yang, C.C.,Niu, C.,Pu, X.,Sun, J.,Zhang, T.,Yang, L.,Zhang, C.,Li, X.,Shen, X.,Xiao, P.,Sun, J.P.,Gong, W. Structural basis of ligand recognition and activation of the histamine receptor family Nat Commun, 15:8296-, 2024 Cited by DOI: 10.1038/s41467-024-52585-yPDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.66 Å) |
Structure validation
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