8YM7
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with JH-45
This is a non-PDB format compatible entry.
Summary for 8YM7
Entry DOI | 10.2210/pdb8ym7/pdb |
Descriptor | Lysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | lsd1, flavoprotein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 90118.66 |
Authors | Zhiyan, D.,Danyan, C.,Hong, J.,Tongchao, L.,Bing, X. (deposition date: 2024-03-08, release date: 2024-05-22) |
Primary citation | Jiang, H.,Tongchao, L.,Bing, X.,Zhiyan, D.,Danyan, C. Discovery of Novel LSD1 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.83 Å) |
Structure validation
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