8YK4

Structure of SARS-CoV-2 RBD and antibody NT-108

Summary for 8YK4

Entry DOI	10.2210/pdb8yk4/pdb
Descriptor	antibody NT-108, single chain Fv fragment, Spike protein S1 (2 entities in total)
Functional Keywords	sars-cov-2, spike, rbd, antibody, igg, scfv, viral protein
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	54018.56
Authors	Anraku, Y.,Kita, S.,Onodera, T.,Sato, A.,Tadokoro, T.,Adachi, Y.,Ito, S.,Suzuki, T.,Sasaki, J.,Shiwa, N.,Iwata, N.,Nagata, N.,Kazuki, Y.,Oshimura, M.,Sasaki, M.,Orba, Y.,Suzuki, T.,Sawa, H.,Hashiguchi, T.,Fukuhara, H.,Takahashi, Y.,Maenaka, K. (deposition date: 2024-03-04, release date: 2025-03-12)
Primary citation	Anraku, Y.,Tadokoro, T.,Suzuki, T.,Sasaki, J.,Hashiguchi, T.,Kita, S.,Shiwa, N.,Iwata, N.,Nagata, N.,Suzuki, T.,Kazuki, Y.,Fukuhara, H.,Oshimura, M.,Sato, A.,Sasaki, M.,Orba, Y.,Sawa, H.,Maenaka, K. Structural Basis for Potent Neutralization Activity of SARS-CoV-2 Antibody, NT-108 To Be Published,
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation