8YD4

CryoEM structure of apo M. tuberculosis ClpP1P2

Summary for 8YD4

• Entry DOI: 10.2210/pdb8yd4/pdb
• EMDB information: 39164
• Descriptor: ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2 (2 entities in total)
• Functional Keywords: mycobacterium tuberculosis, caseinolytic protease system, holoenzymes, antibiotics, bortezomib, hydrolase
• Biological source: Mycobacterium tuberculosis H37Rv; More
• Total number of polymer chains: 14
• Total formula weight: 317032.93

Authors

Zhou, B.,Gao, Y.,Zhao, H.,Chen, X.,He, J.,Zhang, T.,Xiong, X. (deposition date: 2024-02-19, release date: 2025-02-12)

• Primary citation: Zhou, B.,Gao, Y.,Zhao, H.,Chen, X.,He, J.,Zhang, T.,Xiong, X.; Activation mechanism of caseinolytic chaperone-protease system in Mycobacterium tuberculosis by the anti-cancer drug bortezomib; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.69 Å)