8Y7Y

Local structure of HCoV-HKU1A spike in complex with TMPRSS2 and glycan

8Y7Y の概要

• エントリーDOI: 10.2210/pdb8y7y/pdb
• EMDBエントリー: 39026
• 分子名称: Spike glycoprotein, Transmembrane protease serine 2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: hku1a, spike, tmprss2, viral protein
• 由来する生物種: Human coronavirus HKU1 (isolate N1) (HCoV-HKU1); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 330372.50

構造登録者

Wang, H.F.,Zhang, X.,Lu, Y.,Liu, X.,Sun, L.,Yang, H.T. (登録日: 2024-02-05, 公開日: 2024-07-17, 最終更新日: 2024-08-28)

• 主引用文献: Wang, H.,Liu, X.,Zhang, X.,Zhao, Z.,Lu, Y.,Pu, D.,Zhang, Z.,Chen, J.,Wang, Y.,Li, M.,Dong, X.,Duan, Y.,He, Y.,Mao, Q.,Guo, H.,Sun, H.,Zhou, Y.,Yang, Q.,Gao, Y.,Yang, X.,Cao, H.,Guddat, L.,Sun, L.,Rao, Z.,Yang, H.; TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.; Cell, 187:4261-, 2024; PubMed: 38964329; DOI: 10.1016/j.cell.2024.06.016

実験手法

ELECTRON MICROSCOPY (3.24 Å)