8Y4K

Metal Beta-Lactamase VIM-2 in Complex with MBL inhibitor B17

This is a non-PDB format compatible entry.

Summary for 8Y4K

• Entry DOI: 10.2210/pdb8y4k/pdb
• Descriptor: Metal-Beta-Lactamase VIM-2, ZINC ION, 2-[[(3~{R})-6-(azetidin-3-yloxy)-1,1-bis(oxidanyl)-3~{H}-2,1-benzoxaborol-1-ium-3-yl]methyl]prop-2-enoic acid, ... (5 entities in total)
• Functional Keywords: metal binding protein-inhibitor complex, metal binding protein/inhibitor
• Biological source: Enterobacteriaceae
• Total number of polymer chains: 2
• Total formula weight: 50050.53

Authors

Li, G.-B.,Wang, S.-Y. (deposition date: 2024-01-30, release date: 2025-02-05, Last modification date: 2025-02-26)

• Primary citation: Liang, G.Q.,Wang, S.Y.,Li, G.B.; Discovery of 2-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)methyl)acrylic acids as potent MBL inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)