8Y4E

Crystal structure of SARS main protease in complex with Bofutrelvir

Summary for 8Y4E

• Entry DOI: 10.2210/pdb8y4e/pdb
• Related PRD ID: PRD_002347
• Descriptor: 3C-like proteinase nsp5, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein
• Biological source: Severe acute respiratory syndrome-related coronavirus (SARS-CoV)
• Total number of polymer chains: 2
• Total formula weight: 67038.60

Authors

Lin, C.,Wang, W.W.,Zhang, J.,Li, J. (deposition date: 2024-01-30, release date: 2025-01-08)

• Primary citation: Lin, C.,Wang, W.W.,Zhang, J.,Li, J.; Crystal structure of SARS main protease in complex with Bofutrelvir; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.04 Å)