8Y0S

Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor

This is a non-PDB format compatible entry.

Summary for 8Y0S

• Entry DOI: 10.2210/pdb8y0s/pdb
• Descriptor: Metallo-beta-lactamase type 2, ZINC ION, 3-[2-azanyl-5-[2-cyclohexylethyl-[3-(4-methylphenoxy)propyl]amino]phenyl]propanoic acid, ... (4 entities in total)
• Functional Keywords: beta-lactamase inhibitor, antibiotic, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Serratia marcescens
• Total number of polymer chains: 4
• Total formula weight: 103964.87

Authors

Kamo, T.,Kuroda, K.,Nimura, S.,Guo, Y.,Kondo, S.,Nukaga, M.,Hoshino, T. (deposition date: 2024-01-23, release date: 2024-02-14)

• Primary citation: Kamo, T.,Kuroda, K.,Nimura, S.,Guo, Y.,Kondo, S.,Nukaga, M.,Hoshino, T.; Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)