8XRP
The Cryo-EM structure of IL-12, receptor subunit beta-1 and receptor subunit beta-2 complex
Summary for 8XRP
Entry DOI | 10.2210/pdb8xrp/pdb |
EMDB information | 38609 |
Descriptor | Interleukin-12 subunit alpha, Interleukin-12 subunit beta, Interleukin-12 receptor subunit beta-2, ... (6 entities in total) |
Functional Keywords | il-12, il-12rb1, il-12rb2, receptor complex, cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 16 |
Total formula weight | 476826.49 |
Authors | Chen, H.Q.,Wang, X.Q.,Ge, X.F.,Zeng, J.W.,Wang, J.W. (deposition date: 2024-01-07, release date: 2024-07-24, Last modification date: 2024-08-21) |
Primary citation | Chen, H.,Ge, X.,Li, C.,Zeng, J.,Wang, X. Structure and assembly of the human IL-12 signaling complex. Structure, 2024 Cited by PubMed: 39111304DOI: 10.1016/j.str.2024.07.010 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.75 Å) |
Structure validation
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