8XQ1

Crystal structure of spleen tyrosine kinase(SYK) in complex with SKI-G-1673

This is a non-PDB format compatible entry.

Summary for 8XQ1

• Entry DOI: 10.2210/pdb8xq1/pdb
• Descriptor: Tyrosine-protein kinase SYK, cyclopropyl-[5-[[4-[4-[[(3~{R},4~{S})-3-methoxy-4-oxidanyl-pyrrolidin-1-yl]methyl]-3-methyl-pyrazol-1-yl]pyrimidin-2-yl]amino]-1-methyl-pyrrolo[2,3-b]pyridin-3-yl]methanone (3 entities in total)
• Functional Keywords: signaling protein-inhibitor complex, signaling protein-inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 68807.07

Authors

Bong, S.M.,Lee, B.I. (deposition date: 2024-01-04, release date: 2025-01-15)

• Primary citation: Lee, B.I.; Crystal structure of spleen tyrosine kinase(SYK) in complex with SKI-G-1673; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)