8XPU
Overall structure of the LAT1-4F2hc bound with JPH203
Summary for 8XPU
Entry DOI | 10.2210/pdb8xpu/pdb |
EMDB information | 38561 |
Descriptor | Isoform 5 of Amino acid transporter heavy chain SLC3A2, Large neutral amino acids transporter small subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | transporter, slc family, inhibitor, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 129517.65 |
Authors | |
Primary citation | Hu, Z.,Yan, R. Structural basis for the inhibition mechanism of LAT1-4F2hc complex by JPH203. Cell Discov, 10:73-73, 2024 Cited by PubMed: 38956038DOI: 10.1038/s41421-024-00697-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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