8XP4

Crystal Structure of human lysyl-tRNA synthetase with acetyllysine

Summary for 8XP4

• Entry DOI: 10.2210/pdb8xp4/pdb
• Descriptor: Lysine--tRNA ligase, N(6)-ACETYLLYSINE (3 entities in total)
• Functional Keywords: ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 120770.85

Authors

Zhang, X.,Li, N.,Guo, Y.R.,Ouyang, Z. (deposition date: 2024-01-03, release date: 2025-01-22, Last modification date: 2026-02-04)

• Primary citation: Guo, D.,Li, N.,Zhang, X.,Zhou, R.,He, J.,Ding, X.P.,Yu, W.,Tong, F.,Yin, S.,Wang, Y.,Xu, X.,Wang, L.,Fan, M.,Feng, S.,Liu, K.,Tang, K.,Ouyang, Z.,Guo, Y.R.,Wang, Y.; Co-Translational Deposition of N6-Acetyl-L-Lysine in Nascent Proteins Contributes to the Acetylome in Mammalian Cells; Adv Sci, 12:2403309-, 2025; DOI: 10.1002/advs.202403309

Experimental method

X-RAY DIFFRACTION (2.26 Å)