8XOL
Cryo-EM structure of human ABCC4 with ANP bound in NBD1
Summary for 8XOL
Entry DOI | 10.2210/pdb8xol/pdb |
EMDB information | 38533 |
Descriptor | ATP-binding cassette sub-family C member 4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ... (5 entities in total) |
Functional Keywords | abc transporter mrp, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 154614.86 |
Authors | Zhang, P.F.,Liu, Z. (deposition date: 2024-01-01, release date: 2024-07-17, Last modification date: 2024-09-04) |
Primary citation | Zhu, Y.,Xing, X.,Wang, F.,Chen, L.,Zhong, C.,Lu, X.,Yu, Z.,Yang, Y.,Yao, Y.,Song, Q.,Han, S.,Liu, Z.,Zhang, P. The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 598:1967-1980, 2024 Cited by PubMed: 38886124DOI: 10.1002/1873-3468.14955 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.02 Å) |
Structure validation
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