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8XOL

Cryo-EM structure of human ABCC4 with ANP bound in NBD1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AATP-binding cassette sub-family C member 4polymer1325149693.91UniProt (O15439)
Pfam (PF00664)
Pfam (PF00005)
In PDB
Homo sapiens (human)MRP/cMOAT-related ABC transporter,Multi-specific organic anion transporter B,MOAT-B,Multidrug resistance-associated protein 4
2APHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
3A2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diolnon-polymer516.88Chemie (DU0)
4APALMITIC ACIDnon-polymer256.41Chemie (PLM)
5AMAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight149693.9
Non-Polymers*Number of molecules11
Total formula weight4920.9
All*Total formula weight154614.9
*Water molecules are not included.

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PDB entries from 2024-10-16

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