8XF6

Cryo-EM structure of integrin ITGAV, ITGB3 and Cilengitide TFA complex, conformation 2

This is a non-PDB format compatible entry.

Summary for 8XF6

• Entry DOI: 10.2210/pdb8xf6/pdb
• EMDB information: 38299
• Descriptor: Integrin alpha-V, Integrin beta-3, 2-[(2~{R},5~{R},8~{S},11~{S})-11-(3-carbamimidamidopropyl)-7-methyl-3,6,9,12,15-pentakis(oxidanylidene)-5-(phenylmethyl)-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]ethanoic acid (3 entities in total)
• Functional Keywords: membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 203894.87

Authors

Xi, Z. (deposition date: 2023-12-13, release date: 2024-12-18)

• Primary citation: Xi, Z.; Cryo-EM structure of integrin ITGAV, ITGB3 and Cilengitide TFA complex, conformation 2; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)