8XA4

A35 of MPXV in complex with mAb981

Summary for 8XA4

Entry DOI	10.2210/pdb8xa4/pdb
EMDB information	38194
Descriptor	Protein OPG161, Heavy chain of mAb981, Light chain of mAb981 (3 entities in total)
Functional Keywords	recombination, replication, viral protein
Biological source	Monkeypox virus More
Total number of polymer chains	4
Total formula weight	65358.11
Authors	Li, Y.N.,Shi, T.H.,Yan, R.H. (deposition date: 2023-12-01, release date: 2025-06-04, Last modification date: 2025-12-17)
Primary citation	Ju, B.,Liu, C.,Zhang, J.,Li, Y.,Yang, H.,Zhou, B.,Huang, B.,Ma, J.,Lu, J.,Cheng, L.,Cong, Z.,Zhu, L.,Shi, T.,Sun, Y.,Li, N.,Chen, T.,Wang, M.,Tang, S.,Ge, X.,Zhao, J.,Tan, W.J.,Yan, R.,Xue, J.,Zhang, Z. Structurally conserved human anti-A35 antibodies protect mice and macaques from mpox virus infection Cell(Cambridge,Mass.), 188:6253-, 2025 Cited by DOI: 10.1016/j.cell.2025.08.005 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.08 Å)

Structure validation