8X79

MRE-269 bound Prostacyclin Receptor G protein complex

8X79 の概要

• エントリーDOI: 10.2210/pdb8x79/pdb
• EMDBエントリー: 38095
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,GNAS complex locus,GNAS complex locus, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: agonist, complex, lipid receptor, signaling protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 131666.97

構造登録者

Wang, J.J.,Jin, S.,Zhang, H.,Xu, Y.,Hu, W.,Jiang, Y.,Chen, C.,Wang, D.W.,Xu, H.E.,Wu, C. (登録日: 2023-11-23, 公開日: 2024-03-06)

• 主引用文献: Wang, J.J.,Jin, S.,Zhang, H.,Xu, Y.,Hu, W.,Jiang, Y.,Chen, C.,Wang, D.W.,Xu, H.E.,Wu, C.; Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs.; Sci Adv, 10:eadk5184-eadk5184, 2024; PubMed: 38335293; DOI: 10.1126/sciadv.adk5184

実験手法

ELECTRON MICROSCOPY (2.41 Å)